Amorolfine
Indications for use
- Treatment of mild cases of distal and lateral subungual onychomycoses due to dermatophytes, yeasts and moulds; max 2 nails
Age
- 18 years +
Dose/directions
- Apply once weekly to the affected nail(s)
Duration
- Finger nails may need treated for 6 months whereas toe nails may require treatment for 9-12 months
- Reassess every 3 months
Contra-indications/referral criteria
- Hypersensitivity
- Peripheral circulatory disorders, diabetes mellitus, immunosuppression
- Patients with nail dystrophy and destroyed nail plate
- Pregnancy and breastfeeding (insufficient data on use)
Examples of drug interactions
- No interaction studies performed
Side-effects
- Rare; may include nail disorders (e.g. nail discolouration, broken nails, brittle nails) and skin reactions (e.g. contact dermatitis, erythema, pruritus) at the application site
Other pertinent information
- SmPCs for various products now state that after application, an interval of an least 10 minutes should be respected before application of any cosmetic nail lacquer. Before repeat application, the cosmetic nail lacquer should be removed carefully (this guidance does not apply universally; check the individual manufacturer's guidance prior to providing any advice on cosmetic nail lacquer)
- Files and cleaning pads provided in pack are not for use on healthy nails
- Reclassified POM→P: 2006; P→GSL: 2018 (adults 18+, max 3 ml, max 2 nails). P products available in packs up to 5 ml